This paper describes an experimental platform for approximate knowledge databases called the Approximate Knowledge Database, based on a semantics inspired by rough sets. The implementation is based upon the use of a standard SQL database to store logical facts, augmented with several query interface layers implemented in JAVA through which extensional, intensional and local closed world nonmonotonic queries in the form of crisp or approximate logical formulas can be evaluated tractably. A graphical database design user interface is also provided which (...) simplifies the design of databases, the entering of data and the construction of queries. The theory and semantics for AKDBs is presented in addition to application examples and details concerning the database implementation. (shrink)

Fibroblast growth factor receptors (FGFRs) have been implicated in many developmental and regenerative events, including axial organisation, mesodermal patterning, keratinocyte organisation and brain development. The consensus view that this reflects a role for one or other of the nine known members of the fibroblast growth factor family in these processes has recently been challenged by the suggestion that FGFRs might be directly activated by a much wider range of ligands, including heparan sulphate proteoglycans and neural cell adhesion molecules. In addition, (...) two novel soluble ligands for FGFRs have been identified using yeast two‐hybrid technology. Overall, the new findings suggest that in terms of ligand binding the FGFRs might be an even more promiscuous family of receptor tyrosine kinases than was already appreciated. (shrink)

00 Drawing on the phenomenological tradition in the philosophy of science and philosophy of nature, Patrick Heelan concludes that perception is a cognitive, ...

This paper investigates the difficulties of creating economic, social, and environmental values when operating as a hybrid venture. Drawing on hybrid organizing and sustainable business model research, it explores the implications of alternative forms of business model experimented with by farmer owned, fairtrade social enterprise Cafédirect. Responding to changes and challenges in the market and societal environment, Cafédirect has tried multiple business model innovations to deliver on all three forms of value capture, with differing levels of success. This longitudinal case (...) study, therefore, provides a contribution to our understanding of how business models enact hybrid mission, providing a platform for triple-bottom-line value capture. In doing so, we are able to expand on the normative understandings of integrating hybrid objectives, and the complications of multiple types of value capture. (shrink)

This richly textured book bridges analytic and hermeneutic and phenomenological philosophy of science. It features unique resources for students of the philosophy and history of quantum mechanics and the Copenhagen Interpretation, cognitive theory and the psychology of perception, the history and philosophy of art, and the pragmatic and historical relationships between religion and science.

IN A recent work I have attempted to show that visual space tends to have a Euclidean geometrical structure only when the environment is filled with a repetitive pattern of regularly faceted objects carpentered to exhibit simple standard Euclidean shapes, and tends to have a hyperbolic structure when vision is deprived of these clues. I conclude that visual perception--and by analogy, all perception--is hermeneutic as well as causal: it responds to structures in the flow of optical energy, but the character (...) of its response is also hermeneutical, that is, it has the capacity to "read" the appropriate structures in the World, and to form perceptual judgments of the World about which these "speak." The clues that are "read" perceptually as giving a Euclidean visual space are engineered objects, such as streets and buildings with repetitive architectural elements. These scientific artifacts of human culture belong to a family of readable technologies central to the phenomenological and existential-hermeneutical analysis of natural science. (shrink)

Quantum-mechanical event descriptions are context-dependent descriptions. The role of quantum (nondistributive) logic is in the partial ordering of contexts rather than in the ordering of quantum-mechanical events. Moreover, the kind of quantum logic displayed by quantum mechanics can be easily inferred from the general notion of contextuality used in ordinary language. The formalizable core of Bohr's notion of complementarity is the type of context dependence discussed in this paper.

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructor.

The aim of this dissertation is to develop a theory of hope which accounts for the two senses in which hoping is, or should be, practical. The first sense concerns the need to make hopes realizable, while the second captures hope's ability to sustain us and foster growth. My argument is that a pragmatic theory of hope, previously undeveloped, provides a compelling explanation of hope's practicality. In particular, such a theory emphasizes three dimensions of the life of hope--particular hopes, habits (...) of hope, and hopefulness--the interweaving of which accounts for hope's practicality. ;In the Introduction, I discuss the need for a practical theory of hope and then sketch key pragmatic ideas used throughout the dissertation. These include pragmatism's commitment to contextualism as well as the means-end continuum. In Chapters I and II, I discuss the first sense of hope's practicality, i.e., its realizability. I situate hope in the context of the human being as an interactive biological organism, highlighting the roles of intelligence and habits, as well as that of the self understood as the reconstructive dynamic of the organism. I then discuss particular hopes by focusing on their ends, understood as future goods which are arduous but nevertheless possible to realize. Chapter II focuses on habits of hope as the primary means to the realization of particular hopes. I consider three such habits, persistence, resourcefulness, and courage. ;Habits of hope also play an important role in the development of hopefulness. In Chapter III, I discuss the nature of hopefulness, contrasting it with despair and examining how it contributes to the second sense of hope's practicality. I argue that we can develop hopefulness as the regnant habit of the self, nurturing and sustaining us as we meet life's trials. The social nature of hopefulness is emphasized through examples drawn from Stephen King's "Rita Hayworth and the Shawshank Redemption" and John Steinbeck's The Grapes of Wrath. Both works show how hopefulness develops through close interpersonal relationships. ;Chapter IV closes the discussion by highlighting the conditioned nature of hope, pragmatically conceived. I consider alternate theories which focus on unconditioned hopes, but argue that these theories undermine hope's practicality. They transform its conditioned transcendence into an unconditioned transcendence, thereby undermining hope's realizability. (shrink)

Quantum mechanics has raised in an acute form three problems which go to the heart of man's relationship with nature through experimental science: (r) the public objectivity of science, that is, its value as a universal science for all investigators; (2) the empirical objectivity of scientific objects, that is, man's ability to construct a precise or causal spatio-temporal model of microscopic systems; and finally (3), the formal objectivity of science, that is, its value as an expression of what nature is (...) independently of its being an object of human knowledge. These are three aspects of what is generally called the "crisis of objec tivity" or the "crisis of realism" in modern physics. This crisis is. studied in the light of Werner Heisenberg's work. Heisenberg was one of the architects of quantum mechanics, and we have chosen his writings as the principal source-material for this study. Among physicists of the microscopic domain, no one except perhaps Bohr has expressed himself so abundantly and so profoundly on the philosophy of science as Heisenberg. His writings, both technical and non-technical, show an awareness of the mysterious element in scientific knowledge, far from the facile positivism of Bohr and others of his contemporaries. The mystery of human knowledge and human SUbjectivity is for him an abiding source of wonder. (shrink)

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructor.

Today when congressional committees are investigating laboratory notebooks, when the media debate the possibility of cold-fusion, and advertising presents drugs as remedies for everything from infertility to hair loss, the stage is set for the postmodern crisis of confidence in science. This crisis was ushered in by F. Nietzsche, and taken up by M. Heidegger, J. Habermas, Critical Theory, the Strong School of the Sociology of Science, by Margaret Thatcher, on the right and by Jacques Derrida, on the left—and, of (...) course, by the Greens. For so many intellectuals of the population, science has lost its legitimacy as uniquely privileged life-giving knowledge. The spirit of postmodernism in philosophy, as exemplified by Nietzsche, Heidegger, Derrida, Lyotard, and many who claim to be hermeneutic thinkers, has turned against the "master narratives" of our culture which give legitimacy to the institutions of our society and has turned especially against the privileged status of modernist science which is central to this narrative. Since modernism dominates our society mostly through the success and prestige of formal and theoretical systems of codification allied with technical expertise, the most pressing problem for postmodernity then is coming to terms with science and its prevalent modernist interpretation. This is the problem I want to address. 2012 APA, all rights reserved). (shrink)

This is a case study investigating the growth of fair trade pioneer, Cafédirect. We explore the growth of the company and develop strategic insights on how Cafédirect has attained its prominent position in the UK mainstream coffee industry based on its ethical positioning. We explore the marketing, networks and communications channels of the brand which have led to rapid growth from niche player to a mainstream brand. However, the company is experiencing a slow down in its meteoric rise and we (...) question whether it is possible for the company to regain its former momentum with its current marketing strategy. (shrink)

It has been argued that killing persons is wrong because it deprives them of future experiences. Some opponents of abortion argue that the same apples to potential persons—fetuses, zygotes, embryos, etc.—so that to destroy them is as wrong as killing a person. Phil Gosselin rejects this position, employing the reductio argument that if it were so, contraception would be equally wrong, since it destroys potential persons that are gamete pairs. I argue in this paper that Gosselin’s position on the ontological (...) status of the “victim” of contraception, the gamete pair, is flawed in such a way that his conclusion that there is no morally relevant difference between what is destroyed by abortion and what is destroyed by contraception fails. A gamete pair is ontologically different from a fetus; “victims” of contraception and victims of abortion are not significantly analogous, and the reductio that depends upon their similarity for its force is unsuccessful. (shrink)

A significant criticism of the anthropic principle as a scientific claim is that testable predictions cannot be derived from it. Brandon Carter has argued, however, that the principle can be used to predict on the one hand that the period of time biological evolution is intrinsically likely to require is very large, and on the other that the number of ‘critical steps’ that have occurred in the evolution of life on earth is related to the length of time life can (...) continue to evolve. I attempt to show that neither of Carter's arguments provides a convincing defence of the testability of the anthropic principle. (shrink)

Why a hermeneutical philosophy of the natural sciences? It is necessary to address the philosophic crisis of realism vs relativism in the natural sciences. This crisis is seen as a part of the cultural crisis that Husserl and Heidegger identified and attributed to the hegemonic role of theoretical and calculative thought in Western societies. The role of theory is addressed using the hermeneutical circle to probe the origin of theoretic meaning in scientific cultural praxes. This is studied in Galileo's discovery (...) of the phases of Venus; the practice of measurement; the different theories and practices of space perception; the historicality and temporality of scientific research communities which ground paradigm change; and the process of discovery. The paper draws particularly from the work of Heidegger. Though envisaging all science and scholarship, the highlighted theme is research in the natural sciences. (shrink)

Many of the thousands of human embryos currently in cryogenic storage will sooner or later be discarded, often after being experimented upon. Others will remain in storage indefinitely, left there by parents who have no plans either to bring them to term or to offer them for adoption. These facts, coupled with a commitment to the basic moral equality of all human beings at all stages of development, generate a pressing question: What should be done for these embryos whose vital (...) activities have been suspended and whose futures look so bleak? This paper offers a case that allows some of these cryogenically stored embryos to thaw and die, allows disposal of their remains in a manner that reflects their status, and is morally acceptable in that it is consistent with the principles that many accept as governing the removal of life-sustaining treatment in end-of-life cases. (shrink)

This essay is dominated by three themes that recur contrapuntally in Heisenberg’s writings: observation, description, and ontology—prompted always by a concern about the role played by the subjective inquirer in scientific meaning-making, and by the ontology of scientific claims. Among the related themes are; the tension between paradigmatic concerns with structure and philosophical concerns with reality, the possibility of scientific revolutions, such as relativity and quantum mechanics, that can overthrow the classical traditions of natural science and the inadequacy of a (...) psychophysical parallelism for an epistemology of reason. The influence of Husserl and Heidegger is in his neokantian concern about the role of subjectivity. Heisenberg was a long-time friend of Heidegger and familiar with Heidegger’s hermeneutical phenomenology and its critique of Greek philosophy; he also contributed an essay to a Festschrift in Heidegger’s honor in 1959. (shrink)

The classical notion of scientific objectivity is a property of propositional truth. It is the property of being open to testing and inspection, in principle, by all men, although in practice perhaps, the testing of a scientific claim is restricted to the members of a community of professional experts. It is, moreover, the property of being stable in time, true eternally as it were; for objective truth is thought to express what is so independently of human interests, initiatives, bias, social (...) circumstances and historical environment. Often there is the added connotation that what is so is pictured not in its relationship to man, but absolutely, as it were, in itself, or in its relations to the rest of nature, where nature is taken to have an essence independently of the meaning conferred on nature by Dasein. All this is expressed as truth-invariance relative to synchronous communities of knowers whether sympatric or allopatric : truth-invariance relative to allochronous communities of knowers, and truth-invariance relative to the physical transformations and substitutions which define the objective content of a scientific law or theory. (shrink)

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructor.

Heisenberg, in constructing quantum mechanics, explicitly followed certain principles exemplified, as he believed, in Einstein's construction of the special theory of relativity which for him was the paradigm for radical theoretic change in physics. These were the principles of scientific realism, stability of background knowledge, E-observability, contextual re-interpretation, pragmatic continuity, model continuity, simplicity. Fifty years later, in retrospect, Heisenberg added the following two: a principle of non-proliferation of competing theories - scientific revolutions are not a legitimate goal of physics - (...) and a principle of tenacity - existing theories are to be conserved as far as possible. The conservative as well as the revolutionary potential of these principles is then discussed. A more penetrating philosophical criticism of these principles is postponed. (shrink)

Husserl argues in the Crisis that the prevalent tradition of positive science in his time had a philosophical core, called by him "Galilean science", that mistook the quest for objective theory with the quest for truth. Husserl is here referring to Gottingen science of the Golden Years. For Husserl, theory "grows" out of the "soil" of the prescientific, that is, pretheoretical, life-world. Scientific truth finally is to be sought not in theory but rather in the pragmatic-perceptual praxes of measurement. Husserl (...) is faulted for taking measuring processes to be "infinitely perfectible". The dependence of new scientific phenomena on the existence of prior "prescientific" inductive praxis is analyzed, also Husserl's residual objectivism and failure to appreciate the hermeneutic character of measurement. Though not a scientific (theory-)realist, neither was he an instrumentalist, but he was a scientific (phenomena-)realist. (shrink)

Hermeneutics, or interpretation, is concerned with the generation, transmission, and acceptance of meaning within the lifeworld, and was the original method of the human sciences stemming, from F. Schleiermacher and W. Dilthey. The `hermeneutic philosophy' refers mostly to Heidegger. This paper addresses natural science from the perspective of Heidegger's analysis of meaning and interpretation. Its purpose is to incorporate into the philosophy of science those aspects of historicality, culture, and tradition that are absent from the traditional analysis of theory and (...) explanation, to re-orient the current discussion about scientific realism around the hermeneutics of meaning and truth in science, and to establish some relationship between the current philosophy of natural science and hermeneutical philosophy. The paper has particular relevance to the history and social studies of science and technology. (shrink)

Two hundred years ago, Friedrich Schleiermacher took critical issue with Immanuel Kant's intellectual notion of intuition as applied to human nature (Wellmon 2006). He found it necessary to modify—"hermeneutically," as he said—Kant's notion of anthropology by enabling it to include as human the new and strange human tribes Captain Cook found in the Pacific South Seas. A similar hermeneutic move is necessary if physics is to include the local contextual empirical syntheses of relativity and quantum physics. In this hermeneutical revision (...) the synthesis is formed around the notion of a Hilbert Vector Space as the universal grammar of physics, adding to it the dynamic of the Schrödinger equation, and representing empirical "observables" by projection operators that map the subspaces of definite measurable values. Among the set of observable projection operators, some pairs share the same subspace, commute with one another, and share a common laboratory setting. Other pairs do not share this property and are described as being mutually complementary. Complementary symmetries introduce into the discursive language of physics the commonsense notion of contextuality. The new synthesis, proposed by Eugene Wigner, John von Neumann, and (in his own way) Paul Dirac, brought physics into the community of common language and established it as a work of general human achievement. 1. (shrink)

Patrick Aidan Heelan’s The Observable offers the reader a completely articulated development of his 1965 philosophy of quantum physics, Quantum Mechanics and Objectivity. In this previously unpublished study dating back more than a half a century, Heelan brings his background as both a physicist and a philosopher to his reflections on Werner Heisenberg’s physical philosophy. Including considerably broader connections to the contributions of Niels Bohr, Wolfgang Pauli, and Albert Einstein, this study also reflects Heelan’s experience in Eugene Wigner’s laboratory (...) at Princeton along with his reflections on working with Erwin Schrödinger dating from Heelan’s years at the Institute for Advanced Cosmology in Dublin. A contribution to continental philosophy of science, the phenomenological and hermeneutic resources applied in this book to the physical and ontological paradoxes of quantum physics, especially in connection with laboratory science and measurement, theory and model making, will enrich students of the history of science as well as those interested in different approaches to the historiography of science. University courses in the philosophy of physics will find this book indispensable as a resource and invaluable for courses in the history of science. (shrink)

A structural analogy is pointed out between a check hermeneutically developed phenomenological description, based on Husserl, of the process of perceptual cognition on the one hand and quantum mechanical measurement on the other hand. In Husserl's analytic phase of the cognition process, the 'intentionality-structure' of the subject/object union prior to predication of a local object is an entangled symmetry-making state, and this entanglement is broken in the synthetic phase when the particular local object is constituted under the influence of an (...) iota ('inner horizon') and the 'facticity' of the local world ('outer horizon'). Replacing 'perceptual cognition' by 'measurement' and 'subject' by 'expert subject using a measuring device' the analogy of a formal quantum structure is extended to the conscious structure of all empirical cognition. This is laid out in three theses: about perception, about classical measurement, and about quantum measurement. The results point to the need for research into the quantum structure of the physical embodiment of human cognition. (shrink)

The fundamental constants and initial conditions of the universe seem "finely tuned" for human habitation. The anthropic principle attempts to explain this fine tuning in terms of the eventual development of intelligent life. A closer look at the principle’s explanandum, however, reveals that it is teleologically and anthropocentrically biased. Our ignorance of the physical requirements of nonhuman forms of life forces the principle to be more unjustifiably anthropocentric and more speculative than is commonly admitted. Leslie’s, Barrow’s and Tipler’s attempts to (...) avoid an overly anthropocentric anthropic principle fail to solve these problems. (shrink)

. How does the doctrine of double effect apply to business decisions to sell products which may be harmful to consumers? Lawrence Masek believes that some authors have misapplied the doctrine to this type of decision and, as a consequence, have committed themselves to placing unwarranted constraints on businesses. Seeking to correct this mistake, Masek presents his account of how the doctrine applies here, an account which is rather permissive but which, he claims, nevertheless preserves the virtues of the doctrine. (...) It will be seen, though, that his attempt to loosen these putatively unnecessary constraints by appealing to consumer autonomy and an intuition about the morality of producing harmful products leaves the doctrine of double effect irrelevant to this type of decision. His argument that the doctrine is less restrictive in this context than others suppose leads ultimately to the conclusion that the doctrine does not constrain this kind of business decision at all. (shrink)

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructor.